北京市老年人代谢综合征患病率及其与心脑血管病的关系

Metabolic syndrome and its relationship with cardio-cerebral vascular disease among elderly in Beijing area

目的分析北京市老年人代谢综合征(MS)与心脑血管病及性别、随龄的关系。方法于2000年对一个流行病学队列研究人群1827名老年人进行身高、体质量测量及血压和多项血液生化指标的检查,应用中国标准诊断MS,同时进行人口学因素及心脑血管病的调查。结果1827名老年人平均年龄(71±7)岁,代谢综合征(MS组)372例占20.4%。发病率男14.0%,女26.9%,女高于男(P<0.01)。随着年龄增长,MS患病率下降显著。MS组冠心病、脑卒中患病率及男性冠心病患病率、女性脑卒中患病率显著高于非MS组(P<0.05)。80岁以下老人MS组冠心病患病率显著高于非MS组[60～69岁为20.2%vs12.6%(P<0.01);70～79岁为25.0%vs16.2%(P<0.05)];70岁以下MS组脑卒中患病率为13.6%,显著高于非MS组的7.6%(P<0.05)。结论老年人MS患病率高,患有MS的老年人心脑血管病患病率增高,在不同性别及年龄之间存在差异。

Objective To investigate the relationship between metabolic syndrome and cardio-cerebral vascular diseases among difference gender and age in elderly in Beijing area. Methods Totally 1 827 Beijing elderly residents in a cobert study were underwent physical examination in 2000. The indexes included body height, weight, blood pressure and multiple biochemical indicators. The MS was diagnosed based on China criteria. And the demographic data, information of health status were collected and analyzed. Results The survey showed that among 1 827 cases,the mean age was （71 ± 7） years, and 372（20.4% ） cases were diagnosised MS. The incidence was higher in female （26.9%） than in male （14.9%） （P 〈 0.01 ） . With the age grew, the incidence decreased. In MS cases, the prevalence of coronary artery disease especially in male and stroke especially in female, was higher than that of without MS （ P 〈 0.05）. In elderly below 80 years, the prevalence of coronary artery disease was higher in MS cases than others. As for 60 - 69 years old, the incidence was 20.2% in MS cases and 12.6% without MS （ P 〈 0.01）,for 70 - 79 years old,the incidence was 25.0% vs. 16.2% （ P 〈 0.05）. Additional, for below 70 years old, the incidence of stroke was higher in MS cases （13.6%） than others （7.6%, P 〈 0.05） . Conclusion The incidence of metabolic syndrome was high in aged people, and incidence of cardio-cerebral vascular diseases were high in MS cases. The incidence was difference based on age and gender.