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腹腔化疗后腹液中端粒酶检测结果与腹腔转移癌患者预后的关系

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摘要 目的分析腹腔化疗后腹液中端粒酶检测结果与患者预后的关系,了解应用端粒酶评估腹腔转移癌预后的价值。方法68例腹腔转移癌患者,应用端粒末端重复序列扩增—杂交—酶联免疫技术检测腹腔转移癌患者腹腔化疗后腹液中端粒酶,比较端粒酶阳性结果与阴性结果患者24个月生存例数的差别。结果化疗后腹液中端粒酶阳性42例,阴性26例,阳性组患者6、12、18个月的生存率(分别为38.1%、11.9%和2.4%)明显低于阴性组(分别为100.0%、57.7%和26.9%),差异有统计学意义(P<0.01)。24个月生存率差异无统计学意义(P>0.05)。结论检测腹腔化疗后腹液中端粒酶对评估腹腔转移癌患者的预后具有较好的帮助。
出处 《疑难病杂志》 CAS 2009年第4期229-230,共2页 Chinese Journal of Difficult and Complicated Cases
基金 河北省科学技术研究与发展指导计划项目(No.0627611037)
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