实验大鼠结肠电初步观察

A Study of Electrocolonic Activity in Rats

为检测实验性大鼠结肠电的正常值，本研究以埋植电极观察３７只ＳＤ雄性大鼠的结肠电。读图分析发现，禁食情况下大鼠近端、中段和远段结肠都频发０．０８～０．４２Ｈｚ（５～２５ｃｐｍ，即ｃ／ｍｉｎ）的振荡波（ＥＣＡ），近端和中段结肠间断发生０．４２～０．６７Ｈｚ（２５～４０ｃｐｍ）的收缩性复合肌电（ＣＥＣ），而远段结肠的ＣＥＣ则较频繁。大鼠结肠ＥＣＡ的幅值较高，ＣＥＣ的幅值较低。近端结肠的振荡波、远段结肠的ＣＥＣ超过５０％有峰电负载，中段结肠０．０８～０．１７Ｈｚ（５～１０ｃｐｍ）振荡波和０．４２～０．５Ｈｚ（２５～３０ｃｐｍ）的ＣＥＣ超过５０％有峰电负载。大鼠的结肠电及诱发的结肠运动是与其生理功能以及进食和排便习惯相适应的。

olon electrical activities of 37 SD male rats were observed in vivo by implanted electrodes. It was found that electrical control activity(ECA) of 0.08～0.42Hz(5～25cpm)appeared frequently in 3 segments of colon, contractile electrical complex(CEC) of 0.42～0.67Hz(25～40cpm)in distal segment was more than that in proximal and middle segments. The spike of ECA was higher than that of CEC.More than 50% of CEC in distal segment,0.08～0.17Hz(5～10cpm)ECA and 0.42～0.50Hz(25～30cpm)CEC in middle segment had a spike load. The characteristics of colonic eletrical activity and the colonic motility induced are coincident with the physiologic states of the colon and the dietetic and defecation habits.