艾迪注射液辅助选择性的动脉插管化疗治疗中晚期胃癌的临床疗效观察

The Effects of Aidi-injection to Assist Selective Infusion Chemotherapy in Treatment of Advanced Gastric Cancer

[目的]比较艾迪注射液辅助选择性动脉插管化疗治疗(治疗组)与单用选择性动脉插管化疗治疗(对照组)对中晚期胃癌的临床疗效。[方法]选择中晚期胃癌患者56例随机分为两组,治疗组予FAM方案选择性的动脉插管化疗同时加用艾迪注射液,对照组予FAM方案选择性的动脉插管化疗,比较艾迪辅助组和非艾迪辅助组的近期疗效、临床症状、生存质量、不良反应的差异。[结果]治疗组在改善患者生活质量、保护化疗后骨髓功能方面明显优于对照组,差异有统计学意义,P<0.05,且无明显不良反应,对肿瘤疗效两组差异无统计学意义。[结论]艾迪注射液与选择性动脉插管化疗联合应用,疗效显著,可改善患者的生存质量。

[objective] To evaluate the effects of Aidi-injection to assist selective arterial infusion chemotherapy for advanced gastric cancer. [Methods]56 cases with advanced gastric cancer of TNM stage Ⅱ to Ⅲ were randomly divided into two groups. Treatment group（30 cases） received FAM regimen via selective arterial infusion chemotherapy, chemoembolization and Aidi-injection, control group（26 cases） received FAM regimen via selective arterial infusion chemotherapy and chemoembolization. Alleviation and metastasis,clinical symptoms, quality of life and side effects were compared between two groups. [Result] Aidi-injection reduced the sideeffect of chemotherapy, improved physical status（PS） and regulated immunologic function. There was no difference about tumor effective rate between the two groups. [Conclusion]Aidei-injection in combination with seletive infusion chemothevapy has amrked cure effect and can improve life quality.