CA72-4在诊断胃癌中的应用

The value of CA72—4 and CEA in the diagnosis of gastric carcinoma

为进一步判定血清肿瘤标志物糖类抗原７２—４（ＣＡ７２—４）对胃癌的诊断价值，作者对２５例胃癌患者同时测定了血清ＣＡ７２—４及癌胚抗原（ＣＥＡ）水平，并测定了１５例正常人ＣＡ７２—４浓度，结果显示胃癌患者ＣＡ７２—４增高１０例（４０％），ＣＥＡ浓度增高６例（２４％），二者联检阳性率为５６％。胃癌患者血清ＣＡ７２—４水平显著高于对照组。因此认为ＣＡ７２—４是诊断胃癌有价值的指标。

To determine the value of CA72—4 in the diagnosis of gastric carcinoma,we have measured the serum levels of CA72—4 and carcinoembryonic antigen(CEA) simultaneously in 25 patients diagnosed as gastric carcinoma.The percentages of patients whose serum samples is positive for CA72—4 and CEA were 40% and 24% respectively. The data indicates that the measurement of CA72-4 with CEA mayincreases the detectable percentage of gastric carcinoma patients significantly compared with that of either antigen.The findings suggest that CA72—4 is a useful marker for gastric carcinoma diagnosis.