年龄、绝经年限、雌激素水平与妇女血脂关系的探讨

THE RESEARCH AGE,MENOPAUSALAGE,ESTROGEN ON LIPID METABOLISM IN WOMEN

目的了解绝经后妇女（ＰＭＷ）雌激素水平和血脂含量，探讨年龄、绝经年限、雌激素水平与妇女血脂的关系。方法取２７３例绝经前、后及绝经期妇女的空腹血，测定血脂及雌二醇（ＴＣ）、甘油三脂（ＴＧ）、低密度脂蛋白（ＬＤＬ）含量。结果血脂及ＴＣ，ＴＧ，ＬＤＬ与年龄、绝经年限呈正相关，高密度脂蛋白（ＨＤＬ）与年龄、绝经年限无相关性；而雌激素水平与ＴＣ，ＴＧ，ＬＤＬ呈负相关，与ＨＤＬ无相关性。结论ＰＭＷ血脂含量不仅受年龄、绝经年限的影响，且与雌激素水平有关；ＨＤＬ在妇女一生中水平较稳定。雌激素缺乏是ＰＭＷ冠心病发病率上升的原因之一。

Objective To investigate the effect of age,menopausaeage,and estrogen on lipid metabolism in women.Method Plasma totalcholesterd(TC), triglyceride(TG), HDL,LDL and estradiol(E2)were determined in 120 cases of premenopausal,30 cases of perimenopausal and 127 cases of postmenopausal women.Results Age and postmenopausalage were positively related with TC,TG,LDL and were no correlated with HDL.The plesma level of E2 was negatively with TC,TG,LDL and was no correlion with HDL.Conclusions The plasma TC,TG,and LDL are significantly correlated with age, postmeropausalage and the plesma level of es women and the plesma HDL has no changes in the life of the women.