血清F对AFP阴性或低浓度原发性肝癌的诊断分析

Role of Determination of F in the Diagnosis of Primary Liver Cancer in Patients with Negative or Low AFP

为了探讨血清F对AFP不同浓度的原发性肝癌的诊断意义，自1993年1月至1994年12月，对243例原发性肝癌和46例健康对照组进行了血清AFP、F的检测。结果显示：原发性肝癌的血情AFP（＞400μg/L）、F（男＞250μg/L、女>150μg/L）的阳性率分别为47．7%,72．4%，与对照组比较二者差异均有高度显著性（P均＞0．01）。在AFP阴性、低浓度和阳性中F阳性率分别为73．2%（93／127）和71．6（83／116），二者比较差异无显著性（P＞0．05）。结果表明：F对原发性肝癌有诊断意义，尤其对AFP阴性、低浓度的原发性肝癌的诊断具有重要价值。

In outer to measure the levels of serum F and significance in the diagnosis of Primary liver cancer (PLC) Patient with differential concentration of AFP, from January 1993 to December 1994, the measurements Of serum AFP and F were cAned out in 243 cases of Pad and 46 healthy controls. Elevated AFP levels ( > 400 μg/L) and F levels (> 250 μg/L in males and > 150 μg/L in females) were detected respectively in 47 .7% and 72 .4% of 243 Patients with PLC (P even < 0.01 ) .The positive rates of were 73. 2% (93/127) and 71. 6% (83/116) in patients with PLC who had AFP negative lower and positive (P > 0. 05 ). It is suggested that serum F might have important significance in the diagnosis of PLC, espe-.cially for those PLC Patient with negative and lower concentration of AFP.