新型三唑啉酮类化合物的合成及生物活性

Syntheses and Herbicidal Activities of Novel 1,2,4-Triazolinone Derivatives

分别以2,4,5-三氯苯胺和盐酸氨基脲、甲酸为起始原料,设计并合成两个系列新型1,2,4-三唑啉酮类化合物(5,7).通过1H NMR,MS和元素分析确证了其结构,生物活性测定结果表明,化合物5系列的除草效果优良,而化合物7系列则基本没有除草活性,但表现出很强的促进黄瓜子叶生根活性.

Triazolinone herbicides which is environment-benign have a broaden application perspective Several triazolinone compounds such as amicarbazone, sulfentrazone, azafenidin and carfentrazone-ethyl have been developed as herbicides. In order to search for novel 1,2,4-triazolinone derivatives with high herbicidal activities, 2- （ 2,4,5 -trichlorophenyl ） -4- （ 2-substituted-benzyl ） -5 -methyl-2H-1,2,4-triazol-3 （ 4H ） -ones and 2,4-disubstitued-1,2,4-triazol-3 （2H）-ones were designed and synthesized. Their structures were identified by 1^H NMR, MS and elemental analysis. The results of preliminary biological activity tests show that some compounds display excellent herbicidal activity and some display good activity of promoting cucumber cotyledon root-formation at 1.5 kg/ha.