无症状性脑梗塞危险因素的病例对照研究

A case control study of the risk factors of asymptomatic infarction

采用病例对照与多因素分析相结合的方法，调查了３１９例无症状性脑梗塞患者和３１９例对照者，研究无症状性脑梗塞发生的危险因素。条件Ｌｏｇｉｓｔｉｃ回归分析提示，职业、舒张压的增高、体重指数（ｋｇ／ｍ２）、饮食习惯、饮酒指数对该疾病发生的作用无相关性（Ｐ＞０．０５），无症状性脑梗塞发生的主要危险因素依次为单纯收缩期高血压，血粘度增高、冠心病、吸烟指数、脾气暴躁及易激动、糖尿病。结果表明，无症状性脑梗塞的发生是多种因素单独作用和交互作用的结果。单纯收缩期高血压是首位危险因素。

Using a casecontrol method and multiple factors analysis in medical research,319 patients of asymptomatic cerebral infarction(ACI) and 319 controls were investigated.We studied the risk factors of ACI.Conditional Logistic regression analysis showed that there were no significant differences (P>0.05) in the action of occupation,raising the diastolic blood pressure,body weight index(kg/m2),dietetic habit,drinking index on the disease.The main risk factors of ACI were isolated simple hypertension,hyperviscosity of blood,coronary heart disease,cigarette smoking index,irritable temper,and diabetes mellitus.These results suggested that the attack of ACI is the affections of manifold factors,which are interactive as well as independent.Simple systolic hypertension is the chief risk factor.