聚乙烯吡咯烷酮等离子体接枝改性聚丙烯的亲水性及抗凝血性研究

The study of hydrophilicity and anticoagulant properties of polypropylene modified by plasma grafting PVP

采用氩等离子体辅助接枝改性方法在聚丙烯(PP)材料表面接枝水溶性高分子聚乙烯基吡咯烷酮(PVP)。衰减全反射傅立叶红外光谱(FTIR-ATR)和X射线光电子能谱(XPS)分析结果证明PP表面成功地接枝了PVP;接触角测试结果表明表面接枝PVP的聚丙烯表面水接触角相比于未改性的PP,降低了60°,亲水性得到有效改善。采用体外血小板黏附及乳酸脱氢酶实验(LDH)来评价改性前后PP的抗凝血性,评价结果表明表面接枝PVP的聚丙烯表面相比于未改性的PP有较少数量的血小板黏附和激活,表现出良好的抗凝血性。

The research described in this paper presents the surface modification method that water-soluble polyvinyl pyrrolidone （PVP） was grafted onto polypropylene （PP） surface assisted by argon plasma treatment. The analysis of attenuated total reflection Fourier transform infrared spectroscopy （FTIR-ATR） and X-ray photoelectron spectroscopy （XPS） indicated that PVP had successfully grafted onto the surface of PP. The water contact angle of water decreased from 112° of the untreated PP to 52° of PVP-grafted PP, which testified the hydrophilicity of PP effectually improved. The anticoagulant properties were evaluated by in vitro platelet adhesion test and lactic dehydrogenase （LDH） test, and the results showed that adhesion and activation of platelets were significantly reduced by grafting PVP onto the PP surface.