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与过敏性哮喘发生有关的细胞信号转导通路 被引量：3

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作者 夏维 李莉
机构地区 上海交通大学附属第一人民医院检验科
出处 《细胞与分子免疫学杂志》 CAS CSCD 北大核心 2009年第4期371-373,共3页 Chinese Journal of Cellular and Molecular Immunology
基金 国家自然科学基金资助项目(30171200)
关键词 哮喘 信号转导通路 细胞因子 气道炎症
分类号 R392.12 [医药卫生—免疫学]
  • 相关文献

参考文献18

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  • 2Mullings RE, Wilson SJ, Puddlcombe SM, et al. Signal transducer and activator of transcription 6 ( STAT6 ) expression and function in asthmatic bronchial epithelium [ J]. J Allergy Clin Immunol, 2001, 108(5) : 832 -838.
  • 3盛青,何建猷,周爱莲,林晓明.雷公藤甲素对哮喘小鼠信号转导和转录激活因子6及eotaxin表达的影响[J].国际呼吸杂志,2006,26(1):12-15. 被引量：8
  • 4Matsukura S, Stellato C, Plitt JR, et al. Activation of eotaxin gent and Transcription by NF-κB and STAT6 in human airway epitheliel cells[J]. J Immunnol, 1999, 163(12):6876-6883.
  • 5李国平,熊瑛,刘志刚,钟南山.支气管哮喘豚鼠气道上皮细胞信号转导子与转录活化因子1表达及其对气道炎症的调控[J].中华结核和呼吸杂志,2004,27(5):306-310. 被引量：13
  • 6于欣,熊瑛.信号转导及转录激活子-1与支气管哮喘[J].国际呼吸杂志,2007,27(10):758-760. 被引量：4
  • 7Wagner AH, Wittjen I, Stojanovic T, et al. Signal transducer and activator of transcription 1 decoy oligodeoxynucleotide suppression of contact hypersensitivity[ J]. J Allergy Clin Immunol, 2008, 121 ( 1 ) : 158 - 165.
  • 8Gemez Y, Tirouvanziam R, Nguyen KD, et al. Altered phosphorylated signal Transducer and activator of transcription profile of CD4^+ CD161^+ T cells in asthma: Modulation by allergic status and oral corticosteroids[J]. J Allergy Clin Immunol, 2007, 120 (6) : 1441 - 448.
  • 9Edward T, Naureckas, Ndukwu IM, et al. Bronchoalveolar lavage fluid from asthmatic subjects is mitogenic for human airway smooth muscle [J]. Am J Respir Crit Care Med, 1999, 160 ( 12 ) : 2062 - 2066.
  • 10Lee JH, Johnson PR, Roth M, et al. ERK activation and mitogenesis in human airway smooth muscle cells [ J ]. Am J Physiol Lung Cell Mol Physiol, 2001, 280(5) : 1019 - 1029.

二级参考文献22

  • 1申洪.免疫组织化学染色定量方法研究（Ⅲ）[J].中国组织化学与细胞化学杂志,1995,4(1):89-92. 被引量：398
  • 2Xianming Fan~(1,3) Zengli Wang~2 ~1Department of Respiratory Medicine,the Affiliated Hospital of Luzhou Medical College,Luzhou 646000,China,~2Department of Respiratory Medicine,West China Hospital,Sichuan University,Chengdu 610041,China,~3Corresponding to:Dr.Xianming Fan,Department of Respiratory Medicine,the Affiliated Hospital of Luzhou Medical College,Luzhou 646000,China..STAT1 Antisense Oligonucleotides Attenuate the Proinflammatory Cytokine Release of Alveolar Macrophages in Bleomycin-Induced Fibrosis[J].Cellular & Molecular Immunology,2005,2(3):211-217. 被引量：8
  • 3杨礼腾,熊瑛,李国平,孙兴旺,程德云.麻黄调控哮喘豚鼠气道炎症的作用[J].中国呼吸与危重监护杂志,2005,4(6):473-474. 被引量：3
  • 4Takeda K,Tanaka T,Shi W,et al.Essential role of stat 6 in IL4 signaling.Nature,1996,380(18):627-630.
  • 5Wang LH,Yang XY,Kirken RA.Targeted disruption of STAT6 DNA binding activity by an obligonucleotide decoy blocks IL-4 driven Th2 cell response.Blood,2000,95(4):1249-1257.
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  • 7Kuperman D,Schofield B,Wills-Karp M,et al.Signal transducer and activator of transcription factor 6(stat 6)-deficient mice are protected from antigen-induced airway hyperresponsiveners and mucus production.J Exp Med,1998,187(6):939-948.
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  • 9Mullings RE,Wilson SJ,Puddicombe SM,et al.Signal transducer and activator of transcription 5 (STAT6) expression and function in asthmatic bronchial epithelium.J Allergy Clin Immunity,2001,108(5):832-837.
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共引文献32

同被引文献32

  • 1许卓谦,刘志刚,于琨瑛,喻海琼,丘劲.蟑螂变应原诱导小鼠肺部变应性炎症动物模型的研究[J].免疫学杂志,2006,22(5):491-495. 被引量：6
  • 2Patel S P, Jarvelin M R, Little M P. Systematic review of worldwide variations of the prevalence of wheezing symptoms in children [ J ]. Environ Health, 2008,7 (10) :57.
  • 3Flohr C, Tuyen L N, Lewis S, et al. Poor sanitation and helminth infection protect against skin sensitization in Vietnamese children : A cross - sectional study [ J ]. Allergy Clin Immunol, 2006,118 (6) : 1305 - 1311.
  • 4Smits H H, Everts B,Hartgers F C, et al. Chronic hel- minth infections protect against allergic diseases by ac- tive regulatory processes[ J]. Curr Allergy Asthma Rep, 2010,10( 1 ) :3 - 12.
  • 5Flohr C, Quinnell R J, Britton J. Do helminth parasites protect against atopy and allergic disease [ J ]. Clin Exp Allergy 2009,39( 1 ) :20 - 32.
  • 6Smits H H, Hammad H, Nimwegen M, et al. Protective effect of Schistosoma mansoni infection on allergic airway inflammation depends on the intensity and chronicity of infection[ J ]. J Allergy Clin Immunol, 2007,120 ( 4 ) : 932 - 940.
  • 7Pinelli E, Brandes S, Dormans J, et al. Infection with the roundworm Toxocara canis leads to exacerbation of experimental allergic airway inflammation [ J ]. Clin Exp Allergy,2008,38 : 649 - 658.
  • 8Cooper P J. Interactions between helminth parasites and allergy [ J ]. Curr Opin Allergy Clin Immunol 2009,9 (1) :29 -37.
  • 9Guadalupe I, Mitre E, Benitez S, et al. Evidence for in utero sensitization to Ascaris lumbricoides in newborns of mothers with ascariasis [ J ]. J Infect Dis 2009, 199 (12) :1846 1850.
  • 10Djuardi Y, Wibowo H, Supali T, et al. Determinants of the relationship between cytokine production in pregnant women and their infants [ J ]. PLoS One, 2009,4 ( 11 ) : e7711.

引证文献3

二级引证文献10

细胞与分子免疫学杂志
2009年 第4期

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