摘要
目的综述老年抑郁症脑神经环路的变化及影像改变中的应用。方法文献综述法。结果大量的研究表明,老年抑郁症患者存在神经解剖环路(边缘-皮质-纹状体-苍白球-丘脑通路)的改变。结论老年抑郁症核心症状是情感的障碍以及认知功能的改变,老年抑郁症患者神经解剖神经环路功能的异常可通过DTI、MRS、fMRI及其它脑功能成像技术得到证实。
Objective This article briefly reviwed the changes of brain structure of neuroanatomical circuit in late-life depression and the application of radiology. Methods Literrature review. Results Many studies revealed that there were abnormalities function in neuroanatornlcai circuit (limbic-cortical-striatal-pallidal-thalamic tract). Conclusion The maim symptomes of late-life deL pression arc mood disorder and the changes of recognitive function. The changes of neuroanatomical circuit can be confirmed by diffuston tensor Imaging,magnetic resonance spectroscopy,founctional MRI and other brain functional imaging methods.
出处
《中国健康心理学杂志》
2009年第3期366-368,共3页
China Journal of Health Psychology
基金
海南省自然科学基金资助项目(30856)
海南省卫生厅课题(琼卫2007-8)
关键词
老年抑郁症
扩散张量
磁共振波谱成像
功能磁共振戍像
Late-life depression
Diffusion tensor imaging
Magnetic resonance spectroscopy
Founctional MRI