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冠心病患者血浆载脂蛋白B与冠状动脉病变程度的相关性 被引量:5

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摘要 目的:探讨冠心病患者血浆载脂蛋白B(apolipoprotein B,apoB)水平与冠脉病变血管数及冠状动脉Gensini评分的相关性。方法:检测76例冠心病患者(冠心病组)与30例非冠心病者(对照组)血浆中apoB水平,并对冠心病患者进行冠脉造影,记录左主干、左前降支、左回旋支及右冠状动脉4根血管中有几根血管狭窄≥50%。根据冠脉病变血管数将冠心病患者分为3组,单支病变组、双支病变组及三支病变组。结果:冠心病组血浆apoB水平为(1.09±0.26)g/L,明显高于对照组,差异有显著性(P<0.001)。单支病变组、双支病变组、三支病变组及对照组患者血浆apoB水平分别为(0.93±0.21)g/L、(1.02±0.23)g/L、(1.27±0.22)g/L及(0.81±0.19)g/L,4组间血浆apoB水平比较,差异有显著性(P<0.001)。且冠心病患者血浆apoB水平与冠状动脉病变血管数存在正相关,(r=0.397,P=0.029)。冠心病患者血浆apoB水平与冠状动脉Gensini评分无相关性(r=0.084,P=0.635)。结论:冠心病患者血浆apoB水平明显高于非冠心病患者,血浆apoB水平与冠心病冠状动脉病变程度密切相关,积极降低患者血浆apoB水平,对于冠心病的防治可能有重要作用。
出处 《实用医学杂志》 CAS 北大核心 2009年第7期1078-1079,共2页 The Journal of Practical Medicine
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同被引文献31

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