桐花树化学成分的研究

Study on chemical constituents from Aegiceras corniculatum

目的研究桐花树的化学成分。方法采用硅胶柱色谱法分离纯化,薄层色谱及波谱法鉴定结构。结果从桐花树茎皮的乙醇提取物分离得9个化合物,结构鉴定为α-菠甾醇(Ⅰ)、豆甾醇(Ⅱ)、齐墩果酸(Ⅲ)、原报春花素A(Ⅳ)、没食子酸甲酯(Ⅴ)、化合物Ⅵ可能为α-菠甾醇-3-O-β-D-吡喃葡萄糖苷(Ⅵa)和Δ5,22豆甾醇-3-O-β-D-吡喃葡萄糖苷(Ⅵb)的混合物、正三十四烷醇(Ⅶ)、正三十二烷醇(Ⅷ)、没食子酸(Ⅸ)。结论化合物Ⅴ、Ⅵ、Ⅶ、Ⅷ为首次从桐花树茎皮中分离得到。

OBJECTIVE To study the chemical constituents from the stem bark of Aegiceras corniculatum. METHODS The compounds were extracted by alcohol and isolated by silica gel column chromatography, and their structures were elucidated by means of spectral analysis. RESULTS Nine compounds were identified as α - spinastenrol （ Ⅰ ） , stigmasterol （ Ⅱ ） , oleanolic acid （ Ⅲ ） , protoprimula - genin A （ Ⅳ ）, gallic acid methyl ester （ Ⅴ）, stigmasterol 3 - O - β - D - glucopyranoside （ Ⅵa ）, α - spinasterol - 3 - O - β - D - glu - copyranoside（ Ⅵb ）, n - tetratriacontanol （Ⅶ ）, n - dotriacontyl alcohol （Ⅷ） ,gallic acid（ Ⅸ ）. CONCLUSION Compounds Ⅴ, Ⅵ, Ⅶand Ⅷ were isolated from this plant and reported for the first time.