鼻咽癌间质中血管的形态学研究

Observations on the Vascular Pattern in the Interstitium of Nasopharyngeal Carcinoma

本文对疗前鼻咽癌55例和慢性鼻咽炎28例(对照组)的组织切片分别用FⅧ-RAG抗体(PAP法)和UEA(ABC法)标记其血管内皮细胞,并作Gomori氏嗜银纤维染色和VanGieson氏皎元纤维染色。结果显示,间质中血管平均密度与癌实质分化程度和肿瘤某些生长特性有关。鼻咽癌间质中新生血管形态结构和分布状态与慢性鼻咽炎相比育明显不同和持点,这些均为肿瘤细胞迅速生长提供了有利的条件。

Immunohistochemical staining for FⅧ-RAG aud UEA with PAP and ABC technic was used as a marker for vascular endothelial Cells in 55 nasopharyngeal Carcinoma (NPC) and 28 chronic nasopharyngitis (CN). The endothelial cells of vessele gave the positive reaction. The results showed there was close relationship between the amount of blood vessels in the stroma of NPC and the degree of tumor differentiation and growthing made of the tumor. In contrast to CN the NPC blood vessels were irregularity, Sinusoid-like structures, dissorderly running and tapering capillaries. The presence of these Capillaries could be closely related to the tumour growth and also to the invasion of the tumor into surrounding tissue.