放射性肺炎发生的相关因素

Related factors in radiation pneumonitis

放射性肺炎既降低了患者的生活质量，又是胸部肿瘤放疗的剂量限制因素。放射性肺炎是多因素相互作用的结果。剂量体积直方图参数可以用来评价治疗计划的优劣并有效预测放射性肺炎，但是其预测放射性肺损伤的把握度尚欠佳，因此与其他预测因子，如细胞因子联合预测放射性肺炎成为目前研究的热点。

Radiation pneumonitis（RP） not only lowers the patients＇ life quality, but also is one of the common dose-limiting complications in thoracic radiotherapy. RP is the result of many factors, which interacts with each other. DVH parameters can be used to evaluate the treatment plan and to predict RP. But its reliability is not quite sure. Associating other predict factors such as cytokines with DVH parameters to estimate RP has become the current research focus.