敏疏糖胶囊对2型糖尿病外周胰岛素抵抗(痰湿证)患者症状体征的影响

Influence on Therapeutic Effect of Min Shu Tang Capsule in Improving Type 2 Diabetes Patients(Tanshi Syndromes) with Symptoms and Signs of Impact

目的:观察敏疏糖胶囊对2型糖尿病外周胰岛素抵抗(痰湿证)患者的疗效,探索有效的治疗方法,减轻患者的症状体征。方法:采用随机双盲、双模拟、平行对照原则,以2型糖尿病外周胰岛素抵抗中医辨证属痰湿证的患者192例为对象,分为治疗组和对照组,均以格列吡嗪作为基础降糖治疗;治疗组服用敏疏糖胶囊和盐酸吡格咧酮模拟剂治疗;对照组服用盐酸吡格咧酮和敏疏糖胶囊模拟治疗。治疗第0、8、16周分别记录患者症状积分,比较两组疗效。结果:治疗组显效率、有效率,对照组显效率、有效率,治疗组优于对照组,具有显著性差异(P<0.05)。结论:敏疏糖胶囊对2型糖尿病外周胰岛素抵抗(痰湿证)患者症状体征的改善具有较好疗效。

Objective ： Observate Minshutang capsule of the type 2 diabetes peripheral insulin resistance （ Tanshi Syndromes ） in the treatment,and explore effective methods of treatment to reduce the symptoms of patients with signs. Methods： A double- blind, randomized, double-dummy, parallel control principles to type 2 diabetes, insulin resistance weeks TCM is Tanshi card tar- geted at patients with 192 cases, divided into treatment and control groups, are glipizide as the basis Hypoglycemic therapy treat- ment group taking Minshutang capsules Pioglitazone hydrochloride Lie-simulation of the treatment and control group taking Piogli- tazone hydrochloride Lie-and-Minshutang capsule mock treatment. 0,8,16 weeks of the first records of patients with symptoms of points, compared two groups of efficacy. Results ： The remarkable efficiency, efficiency, control group was efficient, effective, the treatment group than the control group ,with significant differences （P 〈 0.05 ）. Conclusion：Capsule on sugar-reduced type 2 dia- betes peripheral insulin resistance （Tanshi Syndromes） in patients with symptoms and signs of improvement with good effect.