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聚乙二醇在器官保存中的应用及作用机制 被引量:4

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摘要 器官移植是根治终末期器官功能衰竭惟一有效的方法,自20世纪60年代在临床应用以来,移植医学已得到了突飞猛进的发展。然而近年来,器官来源短缺已成为阻碍全球器官移植发展的主要问题。为了扩大供者人群,近年来国内外对于边缘供者的利用明显增加,这对传统的器官保存提出了更高的要求。针对传统的UW保存液粘滞度大、钾离子含量高的缺点,国内外学者已对其进行了多种改良,其中聚乙二醇作为替代UW液中羟乙基淀粉(HES)的一种新型大分子物质,已在多种新型器官保存液中得到应用,对器官保存发挥了重要作用。现针对聚乙二醇在器官保存中的应用及作用机制作一综述。
作者 赵闻雨
出处 《中华器官移植杂志》 CAS CSCD 北大核心 2009年第4期252-254,共3页 Chinese Journal of Organ Transplantation
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