老年患者下呼吸道医院感染临床分析

Lower Respiratory Tract Nosocomial Infection A Clinical Analysis in Senile Patients

目的探讨老年患者下呼吸道医院感染的现状,感染病原菌的种类及耐药性,制定预防与控制措施。方法对594例老年下呼吸道感染患者的临床资料进行回顾性调查与分析。结果594例老年患者均患有不同程度的基础疾病,分别进行气管插管、气管切开、机械通气治疗,使用过多种抗菌药物和激素;感染病原菌均为耐药菌,其中铜绿假单胞菌检出率最高,占21.2%;产超广谱β-内酰胺酶(ESBLs)菌总检出率达38.2%。结论尽可能地控制各种能引起的感染环节,从而降低老年患者医院感染的发生。

OBJECTIVE To study the distribution and drug resistance of nosocomial infection pathogens isolated from of lower respiratory tract in senile patients and preventive control measures. METHODS The sputum and lower respiratory tract secretion of 594 senile patients were cultured to detect pathogens which were confirmed by routine methods. Disk diffusion test was used to analyze drug resistance. RESULTS Pseudomonas aeruginosa was the top one （21. 2%）. The drug resistance of Gram-negative organisms were the highest. Extensive-spectrum beta-lactamase （ESBLs） were tested out with 38.2% occurrence. CONCLUSIONS Strictly controI in every step of procedures could reduce nosocomial infection.