摘要
目的了解近年来金黄色葡萄球菌(SAU)医院感染现状及耐药性,为临床诊断疾病与合理使用抗菌药物提供科学依据。方法对321株临床分离的金黄色葡萄球菌的标本分布和科室分布情况进行回顾性调查,采用纸片扩散法进行药物敏感试验,并对结果进行分析。结果SAU对多种抗菌药物产生了不同程度的耐药性,对糖肽类抗菌药物敏感率为100.0%,对新型抗菌药物利奈唑胺敏感率也为100.0%;耐甲氧西林金黄色葡萄球菌分离率达到57.6%。结论SAU对常用抗菌药物显示多药耐药,应对其加强监测与控制。
OBJECTIVE To investigate the antibiotic resistance and nosocomial infections status of Staphylococcus aureus （SAU） and provide scientific evidence for diseasis diagnose and reasonable use of antibiotics. METHODS A retrospective review was performed to analyze the clinical distribution of 321 isolates of SAU. Antibiotic susceptibility test was performed by K-B method and drug-resistance results were analyzed. RESULTS SAU was found been resistant to the diverse antibiotics in different degree. However, the drug sensitivity rate to glycopeptide antibiotics was 100.0%, as well as to new type antibiotic of linezolid. The isolating rate of meticillinresistant S. aureus （MRSA） reached 57. 6%. CONCLUSIONS S. aureus shows multidrug resistance to the commonly used antibiotics. We should strengthen monitoring and controlling of it.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2009年第8期987-989,共3页
Chinese Journal of Nosocomiology
关键词
金黄色葡萄球菌
医院感染
甲氧西林
耐药性
Staphylococcus aureus
Nosocomial infections
Meticillin
Drug resistance
