降压散治疗高血压病300例临床研究

Clinical Study on Jiangya Powder in Treatment of 300 Hypertension Patients

目的观察降压散治疗高血压的疗效。方法将入选患者300例随机分为降压散组(治疗组,153例)和卡托普利组(对照组,147例),观察两组治疗后血压、血脂、血液流变学、肝肾功能及主要症状、体征的变化。结果两组患者收缩压、舒张压均比治疗前明显下降(P<0.05),而且治疗后治疗组明显优于对照组(P<0.05);在症状积分、降低血脂、血液流变学改变方面,治疗后治疗组均明显优于对照组(P<0.05),治疗期间未发现毒副反应。结论降压散是一种安全和有效的治疗高血压的药物。

Objective To observe the effect of Jiangya Powder （Powder for lowering blood pressure） in the treatment of hypertension. Methods The 300 enrolled patients were randomly divided into the treatment group （153 cases treated by Jiangya Powder） and the control group （147 cases treated by Captopril）. Blood pressure, blood lipid, hemorheology, renal and liver functions and main symptoms and signs in both groups were observed before and after treatment. Results In both groups, the systolic pressure and diastolic pressure were both lowered （P〈0.05）, the difference between both groups after treatment was significant, and the decrease of blood pressure in the treatment group was more obvious than that of the control group （P〈（0.05）. The improvement of the treatment group in blood pressure, blood lipid, hemorheology and relieving the main symptoms was both superior to those of the control group, and the difference was significant （P〈0. 05）. There was no any side-reactions found in the duration of treatment. Conelusion Jangya Powder is a safe and effective drug for hypertension.