慢性肺心病血清心肌酶变化与缺氧的关系

Serum myocardial enzyme changes in chronic pulmonary heart disease associated with hypoxia

目的探讨肺心病患者急性期与缓解期,不同缺氧状态下,心肌酶变化与出现肺心病心肌梗死的发生率。方法用酶学动力学测定肺心病急性期54例,缓解期55例的心肌酶的活性,观察心肌酶在两组中的变化与心肌梗死发生率的关系,并观察肺心病心肌梗死的特点。结果正常对照组55例,心肌酶正常;缓解期患者心肌酶基本正常,无心肌梗死发生,急性期患者心肌酶明显高于缓解期患者,且5例发生心肌梗死,差异有统计学意义(P<0.05)。结论慢性肺心病患者心肌酶均有不同程度升高,尤其以急性发作期明显,易并发心肌梗死,且症状不典型,以心功能不全与心律失常表现为主。

Objective To detect myocardial enzyme changes in different state of hypoxia in pulmonary heart disease patients with acute or catabatic stage, and the incidence of myocardial infarction. Methods To measure myocardial enzyme activity in 54 cases of acute pulmonary heart disease, and 55 cases of catabatic stage by enzyme dynamics. And observe the relationship between the myocardial enzymes changes in the two groups with the incidence and the characteristics of myocardial infarction. Results Myocardial enzymes were normal in control group and catabatic stage. Compared with patients in acute stage, myocardial enzymes were significantly higher than patients in remission, and 5 cases occurred myocardial infarction （ P 〈 0. 05 ）. Conclusion Myocardial enzymes had increased with varying degrees, especially in the acute stage of chronic pulmonary heart disease patients, and easy with myocardial infarction, which had untypical symptoms and mainly with heart failure and arrhythmia.