维吾尔族与汉族女性冠心病患者冠状动脉病变的比较

Comparison of coronary artery lesions in female patients with coronary artery disease between Han nationality and Uygur nationality

目的探讨维吾尔族和汉族女性冠心病患者冠状动脉(冠脉)病变的差异。方法回顾性分析经冠脉造影确诊为冠心病女性患者676例,按不同民族分为两组,其中维吾尔族组343例,汉族组333例。冠脉病变程度由病变支数、部位、病变分型及Gensini总积分表示。结果 (1)两组A型病变率最高,维吾尔族低于汉族组(44.6%比64.8%),维吾尔族组B型、C型病变率(29.2%和26.2%)高于汉族组(15.0%和20.2%),差异均有统计学意义(均为P<0.05)。(2)维吾尔族组三支病变(36.4%)高于汉族组(28.2%),而单支病变(36.2%)低于汉族组(47.4%),差异有统计学意义(均为P<0.05)。(3)两组患者Gensini总积分随着年龄增长而增高,相同年龄段,维吾尔族组Gensini总积分均高于汉族组。结论冠脉病变程度随年龄增长而增高,单支病变逐渐减少,三支病变逐渐增加。维吾尔族女性冠心病患者三支病变率高,C型病变多,冠脉病变严重程度较汉族女性重。

Objective To compare the characteristics of coronary artery lesions in female patients with coronary artery disease （CAD） between Han nationality and Uygur nationality. Methods A total of 676 female patients with CAD were analyzed retrospectively and were divided into Uyghur group （n = 343） and Han group （ n = 333 ） according to nationality. Coronary artery lesions and Gensini score were compared between the two groups. Results （ 1 ） Type A lesion occurred less common （44. 6% vs. 64. 8% ） and type B and type C lesion occurred more common in Uygur nationality group than in Han nationality group（ 29. 2% vs. 15.0% and 26. 2% vs. 20. 2% , all P 〈 0. 05 ）. （2）Compared with Han nationality group, the incidence of three-vessel disease was significantly higher （36.4% vs. 28.2% , P 〈0. 05） and the incidence of single-vessel disease was significantly lower （ 36.2% vs. 47.4% , P 〈 0. 05 ） in Uygur group. （ 3 ） Gensini score of Uygur group were significantly higher than those of Han group. Conclusions Severity of coronary artery disease is increased with age. Uygnr women patients have more severe coronary artery lesions, more type C lesions, and have suffered from a higher rate of three-vessel disseases than Han women patients.