硝普钠、多巴胺联合治疗急性左心衰竭70例

Combination Use of Sodium Nitroprusside and Dopamine in 70 Cases of Acute Heart Failure

目的硝普钠、多巴胺微量泵联合治疗急性左心力衰竭疗效观察。方法共观察70例,所有患者常规给予一般治疗,硝普钠起始剂量6.25～12.5μg/min,平均剂量为12.5～50μg/min。多巴胺起始剂量为2μg/(kg·min),平均剂量3～5μg/(kg·min),两药均以微量泵静脉持续输入,硝普钠使用时避光,疗程7～10 d。结果有效43例,有效率61.4%;显效23例,显效率32.8%,总有效率94.2%;心功能无明显改善4例,占5.7%。结论硝普钠、多巴胺微量泵联合治疗急性左心衰竭有效率达94%,能有效地控制症状,用药量小,合并症少,安全可靠,疗效最佳,不失为急性左心力衰竭者较好的治疗方法。

Objective To observe the effect of combination use of Sodium Nitroprusside and Dopa- mine in treatment of patients with acute heart failure. Methods Seventy patients with acute heart failure were treated with Sodium Nitroprusside by microinfusion pump at a dosage of 12.5-50μg/min and Dopamine 3-5μg/ （kg·min） for 7-10 days. The initial dose of Sodium Nitroprusside and Dopamine were 6.25-12.5μg/min and 2 μg/ （kg·min） respectively. Results Fourty-three cases were effective, and 23 cases were markedly effective, and 4 cases were ineffective. The total effective rate was 94.2%. Conclusions Combination use of Sodium Nitroprusside and Dopamine was an effective therapy in treatment of acute heart failure with clinical safety.