经纤维支气管镜诊断肺癌737例分析

Analyses of 737 Cases with Lung Cancer Diagnosed by Fibrobronchoscope

目的研究肺癌与性别、年龄、生长方式的关系,以及钳检和刷检对纤维支气管镜诊断肺癌的意义。方法对2006年11月—2008年10月经纤维支气管镜活检或刷检并经病理诊断的737例肺癌进行回顾性分析。结果737例肺癌中,鳞癌370例,腺癌155例,小细胞癌169例,未定型癌43例。鳞癌中男性336例,女性34例,<60岁145例,≥60岁225例,管腔内增生型260例,管壁浸润型136例,正常型1例;腺癌中男性84例,女性71例,<60岁89例,≥60岁66例,管腔内增生型49例,管壁浸润型110例,正常型3例;小细胞癌中男性126例,女性43例,<60岁89例,≥60岁80例,管腔内增生型51例,管壁浸润型125例,正常型0例。钳检阳性727例,刷检阳性174例。结论鳞癌是肺癌中最为常见的一个类型,多见于老年男性,以管内增生型多见;腺癌多见于中青年女性,以管壁浸润型多见;小细胞癌与性别年龄无关,以管壁浸润型多见;钳检阳性率高于刷检阳性率,钳检刷检联合应用,能提高病理诊断的阳性率。

Objective To study the relationship between lung cancer and sex, age and growth pattern, and to study the significance of biopsy and to brush lung cancer diagnosed by fibrohronchoscope. Methods We analyzed retrospectively the fibrobronchoscope in data of 737 lung cancer patients diagnosed pathologically through transbronchial lung biopsy or brushing. Admove SPSS 13.0 software for Х^2 test for statistical analyses. Results In data of 737 lung cancer patients, squamous cancers were 370, adenocarcinomas were 155, small cell lung cancers were 169. In squamous cancers, males were 336, females were 34, 〈 60 ages were 145,≥60 ages were 225, the intraductal hyperplasia types were 260, the tubal wall infiltrating types were 136, the normal type was 1; in adenocarcinomas, males were 84, females were 71, 〈 60 ages were 89, 〉160 ages were 66, the intraductal hyperplasia types were 49, the tubal wall infiltrating types were 110, the normal types were 3; in small cell lung cancers, males were 126, females were 43, 〈 60 ages were 89, ≥60 ages were 80, the intraductal hyperplasia types were 51, the tubal wall infiltrating types were 125, the normal types were 0. The masculine number of biopsy were 727, the masculine number of brushing were 174. Conclusion Squamous cancer is the most common type in lung cancers, which are much in the older males and the intraductal hyperplasia type; adenocarcinoma is much in middle-aged females and the tubal wall infiltrating type;small cell lung cancers have nothing to do with sex and age, but it is much in the tubal wall infiltrating types. The masculine rate of biospy is higher than that of brushing, union biopsy and brushing may increase the masculine rate of pathologic diagnosis.