92例小儿支原体肺炎的临床观察分析

Invasive Mycoplasma Pneumoniae Infections in Children with Acute Lower Respiratory Tract Infections

目的探讨肺炎支原体(MP)在小儿急性下呼吸道感染(ALRI)中的感染情况,为制订治疗方案提供依据。方法应用病例回顾性分析方法,对2006年11月—2008年5月住院年龄在3个月～14岁、发病在10天以内、确诊为ALRI的368例患儿进行MP-IgM测定,并记录临床资料,进行统计学处理。结果368例患儿中,MP-IgM阳性92例(25%),女童62例,阳性率32.3%;男童30例,阳性率17%,性别差异有统计学意义(P<0.01)。临床症状为100%咳嗽、61%发热,喘息多发生在1岁以内。结论乐清地区小儿ALRI病原体中,MP检出率高,且以女童居多,大环内酯类抗生素疗效确切。

OBJECTIVE Mycoplasma pneumoniae mainly causes acute lower respiratory tract infections （ALRI）, but there is no specific diagnosis in clinic at present. This study was to investigate invasive mycoplasma pneumoniae infections in children with ALRI. METH- ODS By using case retro-speetive method, 368 in-hospital children aged 3 months to 14 years with ALRI seen from November 2006 to May 2008 were tested for mycoplasma pneumoniae IgM antibody. We classified the patients according to the ages, the disease severity and the clinical signs to analyse the results. RESULTS Evidence of acute mycoplasma pneumoniae infection was found in 92 cases（25%）of the 368 children with ALRI, of which 62 cases were female and 30 cases were male, respectively. The number of the female was much higher than that of the male（P〈0.01 ）. Coughs were heard from every children, accounting for 100 percent.Fever accounted for 61 percent. Athma occurred in children who were younger than 1 year old. CONCLUSIONS There were mycoplasma pneumoniae infections in children with ALRI in Yueqing, and prevalence of the infections in girls was much higher than that in boys.