急性脑卒中患者糖代谢异常研究

Study on dysglycemia in the patients with acute stroke

目的探讨急性脑卒中患者糖代谢异常的流行状况。方法将202例新发脑卒中连续病例分为已知糖尿病组和非已知糖尿病组,对所有空腹血糖(fasting plasma glucose,FPG)<7.0mmol/L的非已知糖尿病患者均行糖耐量试验(oral glucose tolerance test,OGTT)。结果急性脑卒中患者糖代谢异常的比例高达66.4%,其中单纯性负荷后高血糖(isolated postprandial hyperglycemia,IPH)为14.4%,单纯性糖耐量受损(isolated impaired glucose tolerance,I-IGT)为23.3%。若不进行OGTT试验,仅依靠检测空腹血糖,将有100%I-IGT患者和80.6%糖尿病患者被漏诊。结论急性脑卒中患者中存在普遍的糖代谢异常,糖耐量试验是及时发现I-IGT和IPH的有效方法。

Objective To investigate the profile of dysglycemia in the patients with acute stroke . Methods The fasting blood glucose（FPG） of 202 patients hospitalized with acute stroke was examined,then oral glucose tolerance test（OGTT） was examined in the patients without diabetes mellitus（DM） history whose FPG was less than 7.0 mmol/L . Results The proportion of dysglycemia was 66.4 % in the patients with acute stroke, and the proportion of isolated postprandial hyperglycemia （IPH） was 14.4%. The proportion of isolated impaired glucose tolerance （I-IGT） was 23.3% . Without the use of OGTT, 100% I- IGT and 80.6 % DM would he undiagnosed by FPG detection alone. Conclusion Dysglycemia is common in the patients with acute stroke,OGTT is an effective method to find IPH and I-IGT in time.