短暂性完全遗忘研究进展

Advances in transient global amnesia

短暂性完全遗忘（transient global amnesia,TGA）是一种具有戏剧性特色的疾病，常有生理性和心理性诱发因素，表现为突发的顺行性遗忘，伴反复询问，持续数分钟至数小时后好转。TGA的研究主要集中在病因和病理学机制方面，目前主要有以下几种假说：短暂性脑缺血发作学说、癫痫学说、偏头痛学说、脑静脉缺血或静脉栓塞学说、人格障碍或情绪刺激学说以及其他学说。TGA的预后较好，复发率低，无需特殊治疗措施。文章对TGA的研究进展做了综述。

Transient global amnesia （TGA） is a disease with dramatic manifestations. It is often induced by the physical or psychogenic factors, and is characterized by a sudden onset of anterograde amnesia accompanied by repeated asking of questions, lasting for minutes or hours. The study of TGA mainly focused on the aspects of etiological and pathological mecha- nisms. Currently, there are several following hypotheses： Transient ischemic attack, epilepsy, migraine, cerebral venous ischemia or venous embolism, personality disorder or emotional stimulation. The prognosis of TGA is better with low recurrence rate. No specific treatment is needed. This article reviews the advances in research on TGA.