关于针灸阳性对照研究关键问题的探讨

Study on key problems in the positive control design methods of acupuncture and moxibustion

针对阳性对照设计的针灸研究常见的关键问题进行了探讨,以期对临床研究有所借鉴。本文从阳性对照的定义、对照形式、统计设计类型、阳性药物的恰当使用、适当采用安慰对照研究的对照方法以弥补研究的不足,合理选择观察指标以凸显中医特色方面进行了探讨,指出只有对这些关键问题在研究中给予充分考虑,才能获得高质量、具有说服力的针灸临床证据。

To probe into the design method of the clinical studies with positive control of acupuncture and moxibustion, the several key problems are analyzed, which include the definition of positive control, form of the control, statistical and design types, proper application of positive drugs, and properly use placebo control method to counteract weaknesses of studies, reasonably select observation indexes so as to show characteristics of Chinese medicine. The authors indicate that only fully thinking these key problems, can provide clinical evidence of acupuncture and moxibustion with high quality and convincingness.