康脉软胶囊治疗动脉硬化闭塞症40例

Treatment of Atherosclerosis Obliterans by Kangmai(康脉) Soft Capsule

目的:观察康脉软胶囊对动脉硬化闭塞症患者的治疗效果,并探讨其作用机理。方法:80例患者随机分为两组,治疗组40例,应用康脉软胶囊治疗。对照组40例,应用通塞脉片治疗。观察治疗前后两组患者血液流变学、踝肱指数、足背温度及临床症状和体征的变化。结果:康脉软胶囊对动脉硬化闭塞症患者有较好的疗效,与对照组比较差异有显著性(P<0.05)。结论:康脉软胶囊通过改善血液流变学,可以有效治疗动脉硬化闭塞症。

Objective To study the clinical effect and mechanism of Kangmai（康脉） Soft Capsule（KMSC） in treating atherosclerosis obliterans（ASO）. Methods Eighty patients with ASO were randomly divided into 2 groups, 40 patients in the control group were treated with Tongsaimaipian（通塞脉片）（TSMP）, the other 40 patients in the treatment group were treated with KMSC. Changes of hemorrheologic indices, ankle brachial index（ABI）, temperature centigrade of the dorsum of foot and clinical sighs and symptoms of both groups were observed. Results KMSC had good therapeutic effect on patients with ASO, with significant difference as compared with the control group（ P 〈 0.05）. Conclusion KMSC through mitigating hemorrheologic mechanism, can treat ASO effectively.