B超评估凝胶和多孔聚乙烯义眼台重建无眼眼眶(英文)

Gel and porous polyethylene implants for anophthalmic cavity reconstruction-evaluation using the B scan ultrasound

目的:运用B超评估受体对无眼眼眶植入凝胶聚乙烯义眼台和多孔聚乙烯义眼台的反应。方法:兔36只行单侧眼内容物剜除并凝胶聚乙烯义眼台或多孔聚乙烯义眼台植入术,术后每周进行临床检查,术后30,60,90d行B超检查。结果:植入凝胶聚乙烯义眼台的兔除1只外,义眼台全都脱出,可能是凝胶义眼台吸水后体积增大造成的。B超检查显示随访期间凝胶义眼台内部无血管。植入多孔聚乙烯义眼台的兔有5只(27.8%),术后30d发生义眼台脱出。根据B超检查,多孔聚乙烯义眼台显示结构不规则有异质性,回声与血管组织类似。结论:如何确定植入兔无眼眼眶的凝胶聚乙烯义眼台的最佳大小,还需要进一步研究。我们的研究显示,B超能有效评估无眼球眼眶植入的义眼台,为进一步的活体研究提供了有用信息,有可能取代其他评估义眼台血管化的昂贵检查。

AIM：To evaluate the host response of the gel and porous polyethylene implants in anophthalmic cavities using the B scan ultrasound.METHODS： Thirty-six white rabbits underwent unilateral enucleation with placement of gel or porous polyethylene spheres implants. The animals were submitted to clinical examination weekly and to ultrasound evaluation on 30, 60 and 90 days after surgery.RESULTS： All rabbits with gel polyethylene spheres, except one, showed implant extrusion probably because the gel spheres have hydrated and increased in volume. The B ultrasound of the gel polyethylene implant did not show vessels inside during the following period. Five animals （27.8%） with porous polyethylene spheres presented implant extrusion after 30 days of surgery. According to B ultrasound, the porous polyethylene implant showed irregular and heterogeneous architecture and reflective peaks similar to vascularized tissues.CONCLUSION. More studies are required to determine the ideal volume of gel polyethylene implant necessary to correct the diminished orbital content in the anophthalmic cavity. The B ultrasound effectiveness showed in this study for anophthalmic socket implants evaluation provided useful information for further in vivo studies and might substitute expensive methods of implants vascularization evaluation.