摘要
为探讨窄谱中波紫外线(NB-UVB)联合他克莫司软膏治疗寻常型银屑病的临床疗效及安全性,将60例寻常型银屑病患者随机分为NB-UVB治疗组、他克莫司软膏治疗组和NB-UVB结合他克莫司软膏治疗组,其中NB-UVB治疗组给予NB-UVB全身照射。他克莫司软膏治疗组给予0.1%他克莫司软膏,涂搽患处;联合治疗组给予全身NB-UVB照射,患处同日涂搽0.1%他克莫司软膏。用PASI积分评定疗效,观察不良反应。结果联合治疗组总有效率为95%,平均起效时间为5 d,PASI评分显著低于其它两组(P<0.05),而NB-UVB与他克莫司治疗组患者的平均起效时间均在9 d以上,总有效率为分别为75%和80%。得到窄谱中波紫外线(NB-UVB)联合他克莫司软膏治疗寻常型银屑病,可以缩短治疗时间,提高治疗的效果。
To investigate the clinical effect and security of NB-UVB and tacrolimus in patient with psoriasis vulgaris,60 patients were randomly divided into NB-UVB group,tacrolimus group and co-treated group.The clinical effect and security were evaluated by the method of PASI.The total effective rate was 95% and the score of PASI was decreased in co-treated group comparing with other groups.It is Conclused that NB-UVB and tacrolimus can increase the therapeutic efficacy and reduce the time of therapy to the patient with psoriasis vulgaris.
出处
《科学技术与工程》
2009年第8期2142-2144,共3页
Science Technology and Engineering
