疏肝豁痰化瘀法治疗不稳定性心绞痛的临床疗效及对sCD40L的影响

Clinical Study of Xintong Decoction on Patients with Unstable Angina and Impact on sCD40L

目的:观察疏肝豁痰化瘀法治疗不稳定性心绞痛(UAP)的临床疗效以及对sCD40L的影响。方法:共入选60例UAP患者,将所有患者随机分入治疗组(中药+西药)和对照组(单用西药),每组各30例,连续用药治疗4周后进行临床疗效比较和机理探讨。结果:治疗组对心绞痛、中医证候的治疗效果和对照组比较有显著性差异(P<0.05),心电图改善两者无显著性差异,在降低血小板sCD40L活性方面与对照组比较有显著性差异(P<0.05)。结论:疏肝豁痰化瘀法治疗UAP有良好临床疗效,且明显降低sCD40L活性。

Objective：In order to observe the clinical effects and investigate sCIMOL of the formula with soothing the liver, reduce phlegm and absorb clots methods （Xintong decoction）in treating patients with UAP. Methods ：60 cases of patients with UAP were randomly divided into treatment group（ western medicine combined with Xintong decoction） and control group（ simply with western medicine）. All clinical data were compared after 4 weeks＇ treatment. Results ：The treatment group to ease angina, Chinese medicine card marquis, nitroglycerin stopped by was significantly better than the control group（P 〈 0. 05）, there was no difference in improving the electrocardiogram （P 〉 0. 05）, active in the reduction of sCD40L compared with the control group are statistically significant （P 〈 0. 05 ）. Conclusion：Methods of soothing the liver and reducing phlegm and absorbing clots methods（ Xintong decoction）in the treatment of UAP good effect, can significantly improve symptoms and reduce sCD40L activity.