尿Alb、β_2-MG及放射性核素GFR检测评价分肾功能的比较

Evaluation of renal function by urinary Alb,β_2-MG and radionuclide imaging of GFR

应用放射免疫分析法测定27例上尿路梗阻患者患肾尿的微量白蛋白（Alb）、β2-微球蛋白（β2-MG）含量，同时用放射性核素肾动态功能显像法测定其中22例患肾的肾小球滤过率（GFR）。结果显示随肾积水程度加重，Alb、β2-MG含量增高，GFR下降，在轻、中、重度肾积水间的差异有统计学意义（P＜0．05～0．01）。同时探讨了两种检测方法在评价分肾功能上的价值。

The renal function of 27 cases with upper urinary tract obstruction were evaluatied by detection of urinary albumin (Alb),β-Microglobulin,while glomerular filtration rate (GFR) assessed by radionuclide renal dynamic imaging in 22 of the 27 cases. With the severity of the hydronephrosis, the urinary Alb and β2-MG were elevated,but the GFR decreaced. There were significantly differences among mild,moderate and severe hydronephrosis (P＜0.05~0. 01). The methods in evaluating the renal function was discusses.