脑膜瘤的伽玛刀治疗

Gamma knife treatment of meningiomas

使用伽玛刀治疗脑膜瘤病人５２例，随访２８例，随访时间２～２２个月。治疗后８例肿瘤体积缩小，１８例体积不变，２例肿瘤增大；一年后肿瘤生长控制率为９２％。９例出现治疗后放射性脑水肿，包括颅底肿瘤２例，非颅底肿瘤７例。讨论了伽玛刀治疗脑膜瘤的适应症及疗效，认为伽玛刀对肿瘤位于颅底或身体不能耐受手术者是一种较安全有效的方法。

From October 1995 to July 1997, 52 cases of meningioma were treated with gamma knife radiosurgery. Twenty-eight cases were followed up by CT or MR. The follow-up period was from 2 to 22 months. Follow-up imaging evaluation showed tumor size shrinkage in 8 cases, central density decrease in 10 cases, no change in 8 cases and tumor volume increase in 2 cases. The actual 1year tumor growth control rate was 92%. Radiationinduced edema was noted in 9 cases, including 7 cases of the nonbasal tumor and 2 cases of basal one. The indications and efficacy of gamma knife treatment of the meningioma were discussed. Our preliminary experience suggests that gamma knife is an effective and safe technique for carefully selected patients with meningiomas.