鲁米那治疗早产儿颅内出血的研究

A Study of Luminal for Premature Infants with Intracranial Hemorrhage

为了探讨鲁米那治疗早产儿颅内出血的临床价值，对３７例生活力低下的住院早产儿随机分为２组进行对照研究。治疗组２４例静脉注射鲁米那，发生颅内出血１０例，出血校正率４１．６％，死亡３例；对照组１３例行常规治疗，发生颅内出血５例，出血校正率４０．０％，死亡５例。统计学处理，显示两组出血发生率差别无显著性意义（Ｐ＞０．０５）。死亡率差别有显著性意义（Ｐ＜０．０５）。疗效表明鲁米那不能降低早产儿颅内出血发生率，有降低其死亡率，减轻颅内出血严重程度的倾向。

To study the clinical value of Luminal for premature infants with intracranial hemorrhage, thirty seven premature infants poorly viable and hospitalized were divided into two groups. Ten of the twenty four in the treatment group had intracranial hemorrhage, accounting for 42.3%, and three of the ten died. Intracranial hemorrhage occurred in five of the thirteen in the control goup, accounting for 40.0%, and five of them died. A statistic study shows that there was no obvious difference in hemorrhage rate between the two groups ( P >0.05) but in mortality rate between them ( P >0.05). These results suggest that Luminal can decrease the intracranial hemorrhage rate of premature infants and their mortality rate, and improve the severity of intracranial hemorrhage which already occurred in premature infants.