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稻瘟病菌cAMP受体类GPCR的生物信息学分析 被引量：4

Bioinformatic Analysis of cAMP Receptor-like GPCRs in Magnaporthe grisea
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摘要 G蛋白偶联受体(GPCRs)是一类重要的细胞表面受体,通过G蛋白介导着多种生物学途径,其介导的信号转导机制及其作为药物靶标的研究已成为研究热点之一。运用生物信息学的方法,对稻瘟病菌全基因组序列中可能的cAMP类GPCR基因进行了生物信息学分析,为深入研究cAMP类GPCR基因的结构和生物学功能奠定了基础。 G protein-coupled receptors （GPCRs） are a class of important cell surface receptors, which mediate many biological pathways through G proteins. Studies on signal transduction mechanisms mediated by GPCRs and using GPCRs as drug targets have become a new hot area for research. In this study, we analyzed the cAMP receptor-like GPCR genes of Magnaporthe grisea genome sequence through bioinformatics approaches. Our results will facilitate to further understanding the structures and functions of cAMP receptor-like GPCRs.
作者 方坤海 刘文德 王爱荣 吴丽民 王宗华
机构地区 福建农林大学功能基因组学研究中心 福建生物工程职业技术学院
出处 《中国农学通报》 CSCD 北大核心 2009年第7期42-46,共5页 Chinese Agricultural Science Bulletin
基金 教育部博士点基金项目"稻瘟病菌cAMP受体类型的G蛋白偶联受体在cAMP信号途径中的功能研究"(20070389006) 国家自然科学基金项目"稻瘟菌PMK1激活途径中G蛋白偶联受体(GPCRs)的功能研究"(30528017)。
关键词 GPCRS 信号转导 稻瘟病菌 cAMP受体 生物信息学 GPCRs, signal transduction, Magnaporthe grisea, cAMP receptor, bioinformatics
分类号 Q933 [生物学—微生物学]
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参考文献14

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二级参考文献25

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共引文献13

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中国农学通报
2009年 第7期

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