神经导航辅助经蝶窦入路显微手术切除大型侵袭性垂体腺瘤

Neuronavigation-assisted Microsurgical Resection of Large Invasive Pituitary Adenoma by Transsphenoidal Approach

目的探讨经蝶窦入路切除大型侵袭性垂体腺瘤的方法。方法回顾性分析在神经导航辅助下经单鼻孔-蝶窦入路显微手术治疗的37例大型侵袭性垂体腺瘤的临床资料。结果神经导航辅助下,切除肿瘤18例,次全切除12例,大部分切除6例,术后死亡1例。结论神经导航辅助的经蝶窦入路切除大型侵袭性垂体腺瘤具有手术创伤小、相对安全及并发症少等优点,可作为大型侵袭性垂体腺瘤的主要治疗手段之一。

Objective To discuss the resection of large invasive pituitary adenoma by neuronavigation-assisted transsphenoidal approach. Methods The clinical data of thirty-seven patients with large invasive pituitary adenomas was retrospectively analyzed who were performed neuronavigation-assisted operation via transsphenoidal approach. Results Total resection was achieved in 18 patients, and subtotal re- sectidn in 12 patients. One patient died. Conclusion Neuronavigation-assisted transsphenoidal microsurgical resection might be a major choice for the treatment of large invasive pituitary adenoma in that it is minimally invasive and less complicated.