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小而密低密度脂蛋白与动脉粥样硬化性相关疾病 被引量：3

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摘要 动脉粥样硬化是一种由脂质代谢异常、血液凝固失调及与遗传、环境等因素有关的血管慢性炎症共同导致的疾病。多见于40岁及以上的中、老年人。研究结果表明，如果内皮细胞长期反复损伤，导致脂质不断沉积和平滑肌细胞持续性增生，经过一系列复杂的反应和恶性循环最终形成动脉粥样硬化，低密度脂蛋白亚组分富含三酰甘油（TG）的小而密低密度脂蛋白（sdLDL）起了决定性的作用。因此sdLDL被称为致动脉粥样硬化脂蛋白，冠心病独立危险因子等。。
作者 丛辉 王惠民 刘杰
机构地区 南通大学附属医院检验医学中心
出处 《中华老年医学杂志》 CAS CSCD 北大核心 2009年第4期333-336,共4页 Chinese Journal of Geriatrics
基金 国家高技术研究发展计划（863计划）重点资助项目（2007AA042106） 南通市社会发展指导计划资助项目（S8919）
关键词 小而密低密度脂蛋白 动脉粥样硬化性 相关疾病 低密度脂蛋白亚组分 脂质代谢异常 致动脉粥样硬化 独立危险因子 环境等因素
分类号 R686 [医药卫生—骨科学]
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参考文献36

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共引文献11

同被引文献35

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引证文献3

二级引证文献11

中华老年医学杂志
2009年 第4期

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