C／EBPα转录因子与急性髓系白血病
摘要
转录因子C／EBPα调控髓系细胞的正常分化和增殖，体内实验证实C／EBPα功能的丢失将阻断髓系细胞的正常分化，并向急性髓系白血病（AML）的恶性细胞转化。在AML患者中发现C／EBPα功能下调与病变的发展之间有直接的关系。自2001年以来，对于转录因子C／EBPα与AML的发病、发展及预后等的研究已深入到一定程度，我们就近年来的相关研究进行综述。
出处
《中华血液学杂志》
CAS
CSCD
北大核心
2009年第4期282-284,共3页
Chinese Journal of Hematology
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