期刊文献+

肺癌并发肺部感染的病原学及其耐药性分析 被引量:4

Pathogenic and Drug Resistance Analysis of Lung Cancer with Pulmonary Infection
下载PDF
导出
摘要 目的探讨肺癌合并肺部感染的病原学特征及其耐药情况。方法回顾性地分析了104例肺癌合并肺部感染的临床资料。结果肺癌并发肺部感染致病菌以革兰阴性菌、真菌、革兰阳性菌为主,其中革兰阴性菌阳性率达62.1%(36/58)。其中以大肠埃希菌、铜绿假单胞菌、肺炎克雷伯杆菌对多种抗生素耐药较严重。结论肺癌并发肺部感染以革兰阴性细菌最常见,临床上应该根据药敏试验选择抗生素。 Objective To explore the pathogenic and drug resistance of 104 cases of lung cancer with puhnonary infection. Methods It was retrospectively analyzed to the clinical data of the lung cancer with pulmonary infection. Results Most of the pathogens involved in the lung cancer with pulmonary infection was gram negative bacteria(62.1% ), fungi and positive bacteria. In the 36 strains of the gram negative bacteria, Escherichia coli,Pseudomonas aeruginosa,Klebsiella pneumoniae was insensitive to many antibiotics. Conclusion Gram negative bacteria is common in the lung cancer with pulmonary infection,rational choice and application to antibiotics should be in accordance with the drug sensitive test.
出处 《中国现代医生》 2009年第11期56-56,146,共2页 China Modern Doctor
关键词 肺癌 肺部感染 耐药性 Lung cancer Pulmonary infection Drug resistance
  • 相关文献

参考文献7

二级参考文献23

  • 1王浴生.抗生素后效应及其临床意义[J].中国抗生素杂志,1996,21(4):306-315. 被引量:55
  • 2余三贺.医学微生物学[M].北京:人民卫生出版社,1983.167-167.
  • 3徐叔云.中华临床物药学[M].北京:人民卫生出版社,2003.302-320.
  • 4Salonen J, Nikoskelainen J. Lethal infection in patients with hematological malignancies[J] .Eur J Haemtol, 1993,51(2) : 102 ~ 108.
  • 5Masuda N, Sakagawa E, Ohya S, et al. Hypersusceptibility of the Pseudomonas aeruginosa nfxB mutant to beta - lactams due to reduced expression of the ampC beta - lactamase [ J ] . Antimicrob Agents Chemocher, 2001,45(4) : 1284 ~ 1286.
  • 6Hand WL, Corwin RW, Steinberg TH, et al. Uptake of antibiotics by human alveolar macrophages. Am Rev Respir Dis, 1984, 129 (2) :933-940.
  • 7Baldwin DR,Honeyboume D,Wise R. Pulmonary disposition of antimicrobial agents: methodological considerations. Antimicrob Agents Chemother, 1992,36 (6) : 1175-1179.
  • 8Conte PL,Potel G,Peltier P,et al. Lung distribution and pharmacokinetics of aerosolized Tobramycin. Am Rev Respir Dis, 1993, 147(8) : 1279-1282.
  • 9Ragenar N, Karen L, Faulkner, et al. Differentiating meropenem and imipenem/cilastatin. Infect Dis Clin Pract, 1997,6 (2) : 291-296.
  • 10Taylor GD, Buchanan M, Kirklsand T, et al. Bacteremic nosocomial pneumonia, A7-year experience in one institution. Chest,1995,108(3)∶786-787.

共引文献144

同被引文献23

引证文献4

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部