高泌乳素血症与不孕的相关性研究

The study of the relationship between hyperprolactinemia and infertility

目的探讨泌乳素对女性不孕症的影响及治疗效果。方法对640例不孕症患者和270例健康体检者的血清进行泌乳素值测定,并对两结果进行比较,观察接受溴隐亭药物治疗后的情况。结果640例不孕症患者中泌乳素升高的有240例,占37.5%,不孕症组泌乳素浓度显著高于健康体检组(P<0.01)。高泌乳素组经溴隐亭治疗后,泌乳素水平有所下降,临床症状有好转。结论高泌乳素血症是不孕症的重要原因之一,泌乳素测定对不孕症疗效观察有重要意义。

Objective ： The purpose of this study was to investigate the influences and therapeutic effect of femal infertility caused by prolaetinemia. Methods： Prolactine （PRL） was perfomed on serum from 640 patients with female infertility and 270 with health women, the two results of PRL were compared, the clinic cases were observed after bromoeriptin therapy. Results： The results showed that 240 of them had hyperprolactinemia （ 37.5% ） and statistically significant differences among the two groups （ P 〈 0. 01 ）. the PRL was lower and therapeutic effect was better by bromocriptine therapy. Conclusions ： The study showed that hyperpro- laetinemia was one of the leading causes of infertility. It was very important for infertility to examine PRL.