茵陈蒿汤化裁方降脂作用的实验研究

Experimental Study on Hyperlipemia-reducing Action of Yinchenhao Decoction Improved Presuiption(Herba Artemisiae Scopariae, Herba Lysimachiae, etc. )

用Wistar大鼠建立高脂血症动物模型观察了茵陈蒿汤化裁方（IHACD）对大鼠肝脂、血脂和血清丙二醛（MDA）含量的影响。结果表明低剂量组（7．5g／kg·d）和高剂量组（15．0g／kg·d）均能明显降低肝组织胆固醇（TC）的含量，对肝组织甘油三脂（TG）影响不大，类似安妥明的作用．低剂量组能明显提高血清高密度脂蛋白胆固醇与总胆固醇的比值（HDL－C/TC），降低血清TC和TG的含量，后者优于安妥明的作用。两种剂量均能明显降低血清MDA的含量。

The effects of Yinchenhao Decoction Improved Prescription on contents of liver -fat,blood-fat and serum malon aldehyde of rats have been investigated on an animal model ofhyperlipermia symptom of Wistar rat. As a result, both low dose group (7. 5g/kg/d) andhigh dose group (15. 0g/kg/d) could obviously decrease cholesterol content of liver tissues(TC) and have no great effect on glyceryl trifatty acid ester of liver tissues (TG) like atromid-S action. But the low dose group could greatly raise the specific value of serum high density lipoprotein cholesterol to total cholesterol and was superior to atromid-S in decreasing ofTC and TG contents, Both dose groups could decrease serum malon aldehyde content.