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YB-1蛋白在非小细胞肺癌中的表达及意义

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摘要 目的:探讨YB-1蛋白在非小细胞肺癌(NSCLC)中的表达及其临床意义。方法:采用免疫组织化学法检测49例NSCLC患者肺癌组织标本中YB-1蛋白的表达情况并与癌旁组织比较。结果:49例NSCLC中YB-1蛋白在细胞核中的阳性率为49%,且与病理类型、临床分期及有无淋巴结转移呈相关性,而与分化程度、性别及年龄无相关性;YB-1蛋白在正常肺组织中无表达。结论:YB-1蛋白的检测有利于对NSCLC患者的诊断、局部淋巴结转移和预后情况作出客观判断。
作者 孙云晖 黄燕
出处 《中国误诊学杂志》 CAS 2009年第10期2295-2296,共2页 Chinese Journal of Misdiagnostics
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参考文献4

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