曲安奈德在玻璃体切割手术中的作用研究

The Application of the Triamcinolone Acetonide Injection on Vitrectomy

目的:探讨曲安奈德(TA)在玻璃体切割手术(PPV)中的标志作用及术后眼压、视力和黄斑水肿同对照组相比较是否有统计学意义。方法:收集2004年12月至2008年12月行玻璃体切割术患者108例126眼,其中治疗组66眼术中玻璃体腔注入TA,对照组60眼术中未注入TA。术后平均随访6个月,观察两组视力、眼压及黄斑水肿的变化,分析其统计学意义。结果:在玻璃体切割术中,TA黏附在玻璃体皮质中,可以清楚地显示残留玻璃体皮质的部位和范围,易于剥除残留玻璃体的皮质,两组在视力、眼压及黄斑水肿的变化差异无统计学意义。结论:TA可以清晰地标志残留玻璃体,提高手术安全性及成功率,未见明显不良反应。

Objective： To discuss the effect of TA which can demarcate the residue vitreous on vitrectomy and whether there are evident differences on post - operative IOP and visual acuity and macular edema compare with comparison group. Method： Form December 2004 to December 2008,108case （ 126 eyes ） were performed vitrectomy and 66 eyes were divided into study group, 60 eyes were divided into control group. We injected TA 0.5ml into vitreous cavity of study group during the surgery. TA was not used in the eyes of control group. The mean follow - up was 6 months after operation, visual acuity and IOP and macular edema of the two groups were compared and analyzed. Result： The location and coverage of the residual vitreous cortex were clearly shown by TA and the residual vitreous cortex was conveniently to be recognized and removed. There was neither difference in visual acuity,IOP.macular edema before and after operation nor obvious ocular complication related to TA, no evident differences in comparison. Conclusion： TA can demarcate the residue vitreous, can improve the safety and success rate of surgery. No obvious side effects occurred.