膀胱肿瘤抗原检测膀胱癌的临床意义

Clinical implication of BTA test in bladder cancer

目的探讨膀胱肿瘤抗原(BTA)对膀胱癌早期诊断的意义。方法以BTA和尿脱落细胞(VUC)对36例膀胱癌进行对比性检则。结果 BTA的敏感性为44.4%,VUC为16.6%,两者有显著性差异(P<0.01)。在早期膀胱癌,BTA的敏感性为VUC的6倍,进展期是VUC的2.5倍。BTA的特异性为90%。结论 BTA是一种简便、快速、无创伤性的检测方法,敏感性明显高于VUC,尤其在早期膀胱癌中有较高的检测价值。

Objective To detect the clinical implication of bladder tumor antigen(BTA)in the diagnosis of early bladder cancer. Methods The BTA test and voided urinary cytology (VUC) examination were comparatively performed in 36 cases of bladder cancer undergoing surveillance. Results The sensitivity of BTA test for detecting bladder cancer was 44.4%, while that of VUC examination was 16.6% (P<0.01). The sensitivity of BTA test was 6 times of that of VUC examination in the diagnosis of early bladder cancer, 2.5 times in progress bladder cancer. The specificity of BTA test was 90%. Conclusion BTA test was a simple, rapid and non-invasive diagnostic procedure. The sensitivity of BTA test was higher than that of VUC examination. The value of BTA test was superior to that of VUC in the diagnosis of early bladder cancer.