幽门螺杆菌感染的流行病学调查

Epidemiological investigation of helicobacter pylori infection

目的：探讨广州和安徽两地幽门螺杆菌（ＨＰ）感染情况。方法：采用血清流行病学方法，对１２７个家庭进行ＨＰ感染的血清学调查。结果：两地ＨＰ感染率分别为３４．５％和５５．９％（Ｐ＜０．００５），平均抗体水平为１．８４±０．４６和２．０４±０．４７（Ｐ＜０．００１）。父母均为阳性的子女ＨＰ感染率明显高于父母均为阴性的子女（Ｐ＜０．０５）。结论：ＨＰ感染率在两地间有差异。子女ＨＰ感染与父母感染有关。

Objective:To determine the incidence of helicobacter pylori(HP) infection in Guangzhou and Anhui.Methods:Serological examination for HP infection was performed in 127 families.Results:Positive rates of HP infection were 34.0% and 55.9%(P<0.050),the mean antibody levels were 1.84±0.46 and 2.04±0.47(P<0.001) respectively,there was a marked difference between the two areas.The positive rate in children of HPpositive parents was obviously higher than that in children of HPnegative parents(P<0.05).Conclusions:There is a marked difference in the incidence of HP infection between these two areas.The incidence of HP infection among children correlates with infection of their parents.That means HP can spread from person to person.