1Luo J, Chen J, Deng Z L, et al. Wnt signaling and human diseases: what are the therapeutic implications[J]. Lab Invest, 2007, 87(2):97-103
2Clevers H. Wnt/beta-catenin signaling in development and disease[J]. Cell, 2006, 127(3):469-480
3Irene Cappuccio I, Calderone A, Busceti CL, et al. Induction of Dickkopf-1, a Negative Modulator of the Wnt Pathway, Is Required for the Development of Ischemic Neuronal Death[J]. The Journal of Neuroscience, 2005, 25(10):2647-2657
4Glinka A, Wu W, Delius H, et al. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction[J]. Nature, 1998, 391(6665):357-362
5Gonzalez-Sancho JM, Aguilera O, Garcia JM, et al. The Wnt an- tagonist DICKKOPF-1 gene is a downstream target of beta-cate- nin/TCF and is downregulated in human colon cancer[J]. Oncogene, 2005, 24(6):1098-1103
6Chamorro MN, Schwartz DR, Vonica A, et al. FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development[J]. EMBO J, 2005, 24(1):73-84
7Pollheimer J, Loregger T, Sonderegger S, et al. Activation of the Canonical Wingless/T-Cell Factor Signaling Pathway Promotes Invasive Differentiation of Human Trophoblast[J]. Am J Pathol, 2006,168(4):1134-1147
8Yamabuki T, Takano A, Hayama S, et al. Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas[J]. Cancer Res, 2007,67:2517-2525
9Mikheev AM, Mikheeva SA, Rostomily R, et al. Dickkopf-1 activates cell death in MDA-MB435 melanoma cells[J]. Biochem Biophys Res Commun, 2007,352(3):675-680
10Lee AY, He B, You L, et al. Dickkopf-1 antagonizes Wnt signaling independent of betacatenin in human mesothelioma[J]. Biochem Biophys Res Commun, 2004,323: 1246-1250