丹参川芎嗪注射液治疗急性脑梗死的临床疗效观察和对血浆内皮素等水平的影响

Clinical Observation on the Effect of Radix Salivae Miltiorrhizae ligustrazine Injection on the Treatment of Acute Cerebral Infarction Patients and Their Plasma Endothelin

目的:观察丹参川芎嗪注射液治疗急性脑梗死患者的临床疗效。方法:将60例急性脑梗死患者随机分为2组,对照组30例给予川芎嗪注射液静脉滴注治疗,治疗组30例给予丹参川芎嗪注射液静脉滴注治疗,观察治疗前后患者神经功能缺损评分、血浆内皮素(ET)及血液流变学的影响,并进行2组间比较。结果:2组治疗后神经功能缺损评分和血浆内皮素(ET)及血液流变学的影响均有显著性差异(P<0.05)。结论:丹参川芎嗪注射液治疗急性脑梗死疗效好,能发挥抗血栓、保护缺血细胞的作用。

Objective:To observe the clinical effect of Radix Salivae Miltiorrhizae Ligustrazine injection on the treatment of acute cerebral infarction patients.Methods:60 patients were randomly divided into two groups.30 patients in the control group were given a treatment of Ligustrazine intravenous drip while 30 patients in the treatment group were treated with Salivae Miltiorrhizae Ligustrazine intravenous drip.The neurological deficit score,plasma endothelin and blood rheology of the patients in the two groups were observed and compared before and after the treatment.Results:There was a significant difference(P<0.05) in the neurological deficit score,plasma endothelin and blood rheology of the patients after the treatment.Conclusion:Radix Salivae Miltiorrhizae Ligustrazine injection has a good effect on the treatment of the acute cerebral infarction patients and can play a role in anti-thrombus,thrombolysis and the protection of ischemic cells.