睡眠不足及夺眠引起机体生理功能的变化

The changes of physiological functions on inadaquate sleep and sleep deprivation

睡眠不足和夺眠可诱发多种神经行为和生理功能改变。大量研究报道,睡眠结构紊乱/夺眠常与炎症反应相关。睡眠改变取决于不良生活方式、年龄增加及疾病状态等多种因素,而这些因素往往伴随着某些炎症标志物的增加,且某些炎症因子可影响人体的健康。

Inadequate sleep and sleep deprivation can cause numerous neurobehavioral and physiological changes. A number of recent studies have reported associations between disrupted sleep or sleep deprivation and inflammatory responses, although the physiological mechanisms underlying these relationships remains unclear. Alterations in sleep due to lifestyle factors, the aging process, and disease states are all associated with increases in a range of inflammatory markers. Several of these inflammatory processes have been associated with reduced health status. Thus, maintaining adequate sleep duration and quality through good sleep habits and treatment of sleep disorders may reduce inflammatory processes associated with aging and increase the wellness phenotype.